In order to study the disease, mice transgenic (genetically modified) are used. In some mice, the gene encoding the Tau protein is mutated. Among others, the gene encoding the protein amyloid that is transferred. Some mice will suffer mutations in both genes.
Mice that had a mutation in the gene encoding the protein Tau show an appearance of the disease shortly pronounced. Mice that had a mutation in the gene encoding the protein amyloid behave like healthy mice. The mice with mutated genes on the two show a disease exacerbated, well defined.
This does not happen necessarily in the same way in humans, but it shows that amyloid plaques potentiate the disease. The neurofibrilles appear at first, and when the amyloid plaques appear, the disease is triggered.
Mice that had a mutation in the gene encoding the protein Tau show an appearance of the disease shortly pronounced. Mice that had a mutation in the gene encoding the protein amyloid behave like healthy mice. The mice with mutated genes on the two show a disease exacerbated, well defined.
This does not happen necessarily in the same way in humans, but it shows that amyloid plaques potentiate the disease. The neurofibrilles appear at first, and when the amyloid plaques appear, the disease is triggered.
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